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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA4
All Species:
13.64
Human Site:
Y132
Identified Species:
20
UniProt:
O75676
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75676
NP_001006945.1
772
85606
Y132
T
H
L
Y
Q
R
Q
Y
F
K
E
A
E
V
R
Chimpanzee
Pan troglodytes
XP_508900
901
98668
Y259
T
H
L
Y
Q
R
Q
Y
F
K
E
A
E
V
R
Rhesus Macaque
Macaca mulatta
XP_001114877
772
85557
Y132
T
H
L
Y
Q
R
Q
Y
F
K
E
A
E
V
R
Dog
Lupus familis
XP_854926
772
85603
H132
T
H
L
Y
Q
R
Q
H
F
K
E
A
E
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
Y132
T
H
L
Y
Q
R
Q
Y
F
K
E
A
E
V
R
Rat
Rattus norvegicus
Q63531
735
82865
M158
T
R
L
S
K
E
V
M
F
T
E
E
D
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
R126
F
L
A
D
E
N
E
R
A
Y
S
F
C
G
T
Chicken
Gallus gallus
Q5F3L1
789
89022
R138
T
H
L
S
Q
R
E
R
F
S
E
N
E
V
Q
Frog
Xenopus laevis
P10665
733
82620
M158
T
R
L
S
K
E
V
M
F
T
E
E
D
V
K
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
M163
T
R
L
S
K
E
V
M
F
T
E
E
D
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
N360
T
H
L
Y
H
S
E
N
F
E
E
S
R
V
R
Honey Bee
Apis mellifera
XP_395099
910
102507
H163
T
H
L
Y
Q
R
E
H
F
T
E
D
E
V
R
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
I142
S
L
H
Q
R
K
V
I
Y
R
D
L
K
L
E
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
D137
Q
L
G
I
I
Y
R
D
I
K
L
E
N
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
M117
P
S
S
E
S
G
L
M
T
V
K
V
Y
S
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
98.6
96.7
N.A.
95.8
41.3
N.A.
56
64
41
41.9
N.A.
27
45.1
48.1
48.2
Protein Similarity:
100
85.6
98.9
98
N.A.
96.7
60.6
N.A.
71.6
78.4
59
60.3
N.A.
38.9
60.1
64.3
61.8
P-Site Identity:
100
100
100
93.3
N.A.
100
33.3
N.A.
0
60
33.3
33.3
N.A.
53.3
73.3
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
53.3
N.A.
13.3
73.3
53.3
53.3
N.A.
73.3
86.6
53.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
21.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
37.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
0
0
7
0
0
32
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
0
0
0
7
0
0
0
7
0
0
7
7
19
0
0
% D
% Glu:
0
0
0
7
7
19
25
0
0
7
69
25
44
0
7
% E
% Phe:
7
0
0
0
0
0
0
0
69
0
0
7
0
0
0
% F
% Gly:
0
0
7
0
0
7
0
0
0
0
0
0
0
7
7
% G
% His:
0
50
7
0
7
0
0
13
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
7
0
0
7
7
0
0
0
0
7
0
% I
% Lys:
0
0
0
0
19
7
0
0
0
38
7
0
7
0
19
% K
% Leu:
0
19
69
0
0
0
7
0
0
0
7
7
0
7
7
% L
% Met:
0
0
0
0
0
0
0
25
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
0
7
0
0
0
7
7
0
0
% N
% Pro:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
0
7
44
0
32
0
0
0
0
0
0
0
7
% Q
% Arg:
0
19
0
0
7
44
7
13
0
7
0
0
7
0
44
% R
% Ser:
7
7
7
25
7
7
0
0
0
7
7
7
0
7
0
% S
% Thr:
69
0
0
0
0
0
0
0
7
25
0
0
0
0
7
% T
% Val:
0
0
0
0
0
0
25
0
0
7
0
7
0
69
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
44
0
7
0
25
7
7
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _